Antimicrobial resistance (AMR) in livestock production represents a simultaneous welfare, public health, and food security challenge. Routine antibiotic use for growth promotion and mass disease prevention has contributed to resistance in key human pathogens including MRSA, ESBL-producing Enterobacteriaceae, and resistant Campylobacter and Salmonella. WHO classifies several critically important antimicrobials as priority for restricting veterinary use. Welfare intersects with AMR in multiple ways: over-reliance on antibiotics masks poor husbandry; antibiotic withdrawal forces improvement of underlying welfare conditions; resistant infections cause prolonged animal suffering when treatment fails. Denmark reduced total antibiotic use by 40% between 1994-2005 through voluntary reduction programmes while maintaining production, demonstrating feasibility. EU banned antibiotic growth promoters in 2006. Alternatives including vaccines, probiotics, phage therapy, and improved biosecurity support AMR reduction while improving animal welfare.