Ticks and tick-borne diseases represent major welfare and economic challenges in livestock production globally. Rhipicephalus (Boophilus) microplus (cattle tick) causes anaemia, hide damage, and transmits Babesia and Anaplasma pathogens causing fatal disease. East Coast Fever (Theileria parva) transmitted by Rhipicephalus appendiculatus kills over one million cattle annually in sub-Saharan Africa. Welfare impacts include pain from heavy infestations, anaemia, fever, and the neurological symptoms of tick toxicosis. Acaricide resistance is widespread globally, limiting chemical control efficacy. Integrated tick management combines rotational grazing (resting paddocks to reduce tick burdens), strategic acaricide treatment at high-risk periods, biological control using Metarhizium anisopliae fungus, and genetic selection for tick-resistant breeds (Bos indicus breeds show significantly greater resistance than Bos taurus). Vaccination against Babesia species reduces disease burden without eliminating ticks. Welfare monitoring includes regular assessment of anaemia indicators and tick burden scoring.