Sea lampreys are invasive parasites in the North American Great Lakes requiring active control programmes, raising welfare questions about the methods used and the impact on native lamprey species.
Sea lamprey control programmes cause mass mortality of larvae through chemical lampricide application, raising questions about welfare for both target and non-target species. Chemical control with TFM causes death through respiratory failure over several hours. The scale of control is enormous, with millions of larvae killed annually. While control is justified by the ecological and economic damage caused by sea lampreys, ongoing research into species-selective control methods including pheromone-based trapping and barrier exclusion would reduce the welfare impact of control programmes on both sea lampreys and native species.