Chronic kidney disease is the most common serious illness of older cats, requiring long-term management to maintain quality of life.
Cats with CKD experience a range of welfare-compromising symptoms including nausea, dehydration, lethargy, and uraemic toxin accumulation. Nausea from uraemia reduces food intake in a self-reinforcing cycle that accelerates weight loss and muscle wasting. Early detection through regular blood testing allows management to begin before clinical signs appear, substantially improving prognosis and welfare outcomes. Home fluid therapy, when owners are willing and able, provides the most significant welfare benefit by treating dehydration without repeated stressful clinic visits. End-of-life decisions for cats with advanced CKD require careful monitoring of quality of life indicators.