Rabbits are the third most commonly used research animal in the UK, with specific welfare needs related to their social nature, sensitivity to handling, and stress susceptibility.
Research rabbit welfare is characterised by the species' specific vulnerabilities: rabbits have a powerful fear response that causes physiological stress rapidly escalating to life-threatening cardiovascular events in poorly handled individuals. Skilled, confident handling that minimises restraint duration and uses appropriate holds is essential. Social housing — providing rabbit companionship — reduces chronic stress significantly but requires management of social dynamics. Research institutions that invest in staff handling training achieve both better welfare outcomes and better quality research from less-stressed animals.