American bison once roamed North America in tens of millions; today managed herds face unique welfare and genetic challenges.
Bison in managed herds sometimes experience stress from handling, fencing, and reduced ranging opportunities. Genetic bottleneck effects and hybridization with cattle are ongoing conservation concerns. Animals subjected to round-ups for brucellosis testing or culling can experience acute stress. The best welfare outcomes occur in large unfenced landscapes where social herds can self-regulate.