The chytrid fungus Batrachochytrium dendrobatidis has caused the most catastrophic disease-driven vertebrate decline in recorded history, killing billions of amphibians across the world.
Amphibians dying from chytridiomycosis experience a distressing death: electrolyte disruption causes lethargy, muscle cramps, and cardiac failure over days to weeks. The disease has caused individual suffering on a vast scale across wild populations. Captive assurance colonies protect species from extinction but require long-term commitment to species-specific environmental and nutritional needs. Probiotic and antifungal research offers hope for field-based interventions that could reduce disease burden in wild populations.