Mulesing is a surgical procedure performed on Merino sheep without anesthesia to prevent flystrike, causing significant acute pain.
Mulesing causes intense acute pain during the procedure and for weeks afterward as the wounds heal. Lambs show pain indicators including reduced activity, abnormal postures, and elevated cortisol for up to three weeks. Alternative methods including chemical treatments and selective breeding for plain-bodied sheep exist but adoption has been slow due to economic considerations.