Cosmetic and household product safety testing on animals is increasingly restricted globally but persists in many countries.
Animals used in safety testing experience acute and chronic pain from tests designed to identify harmful substances. Eye irritancy tests apply substances directly to restrained rabbit eyes without anesthesia. Repeated dose toxicity studies expose animals to substances causing prolonged organ damage. Skin sensitization tests involve repeated exposure causing dermatitis. These welfare harms continue in countries without testing bans. The availability of validated non-animal alternatives makes continued animal testing unnecessary for most applications.