Second-generation anticoagulant rodenticides are among the most pervasive wildlife poisons in use, killing owls, hawks, foxes, and other predators through secondary poisoning of rodent prey.
Anticoagulant rodenticide poisoning causes prolonged, painful deaths in both target rodents and non-target predators. The welfare cost falls across multiple trophic levels. The conservation and welfare case against SGARs is strong, and some countries have restricted public access while maintaining professional use. Even where legal, the precautionary principle supports preferring alternatives where rodent control is needed indoors. Urban and agricultural use near natural habitats poses the greatest non-target risk.