White-nose syndrome is a fungal disease that has killed over 6 million North American bats, causing mass mortality events in hibernating colonies.
Infected bats wake repeatedly from hibernation, burning through fat reserves needed to survive winter. The final stages involve emaciation, exhaustion, and death in millions of individuals. Cave hibernation sites can lose entire colonies in a single season. The scale of suffering and mortality from white-nose syndrome represents one of the most severe wildlife disease events in recorded history.