Feline leukaemia virus (FeLV) is a retrovirus that causes immunosuppression, anaemia, and cancer in cats, for which vaccination and management of exposure risk are the primary welfare interventions.
FeLV causes progressive welfare deterioration — immunosuppression leads to recurrent infections, anaemia causes lethargy and breathlessness, and eventual lymphoma brings its own welfare burden. Many FeLV-positive cats are euthanised prematurely due to owner anxiety rather than actual welfare impairment. Positive cats can live good lives for extended periods with appropriate management including keeping them indoors to prevent secondary infections and transmission to other cats, regular monitoring, and prompt treatment of secondary conditions. The welfare imperative is to make management decisions based on the individual cat's current quality of life rather than on diagnosis alone.