Myasthenia gravis is a neuromuscular disorder in dogs causing severe muscle weakness, most notably megaoesophagus, and requires long-term management to maintain quality of life.
Myasthenia gravis significantly impairs quality of life through weakness, regurgitation, and the constant risk of aspiration pneumonia. Dogs with megaoesophagus must be fed in an upright position — often using a Bailey chair — for 20-30 minutes after every meal, a significant management burden for owners. Aspiration pneumonia causes pain, respiratory distress, and frequent hospitalisation. Generalised weakness affects mobility and the ability to engage in normal behaviours. With appropriate medical management and feeding modifications, many dogs can maintain acceptable welfare, but the condition demands intensive owner commitment. Early diagnosis and consistent treatment are essential to preventing life-threatening complications.