Leptospirosis is a potentially fatal bacterial disease in dogs with increasing prevalence linked to flooding events and wildlife exposure, requiring vaccination and owner awareness for prevention.
Dogs with severe leptospirosis experience rapid multi-organ failure. Acute kidney injury causes uremia — accumulation of toxins that cause vomiting, lethargy, and neurological signs. Liver failure causes jaundice and coagulopathy. Pulmonary hemorrhage syndrome, increasingly recognized as a manifestation of leptospirosis, causes severe respiratory distress from bleeding into the lungs. Hospitalization requires intensive fluid therapy, antibiotics, and organ support over days to weeks. Many dogs that survive acute illness are left with permanent kidney damage requiring ongoing management. The severity and speed of leptospirosis progression makes early recognition and treatment critical — delays of hours in seeking care can be the difference between survival and death.