Feline immunodeficiency virus is a lifelong infection in cats that, with modern management, allows most FIV-positive cats to live normal, comfortable lives with appropriate care and monitoring.
FIV-positive cats have historically suffered disproportionate welfare harm from misconceptions about the disease. Wholesale euthanasia of FIV-positive shelter cats — once common practice — denied thousands of cats the normal, comfortable lives they could have lived. The social isolation policy (keeping FIV-positive cats strictly separate from all other cats) remains controversial: while it prevents biting-related transmission, it denies cats appropriate social companionship and the welfare benefits of compatible cat relationships. In reality, FIV-positive cats living with other cats in stable, non-aggressive households pose minimal transmission risk. The greatest welfare challenges for FIV-positive cats arise during immunosuppressive phases: secondary oral disease causes significant pain, and respiratory infections that are minor in immunocompetent cats can become serious. Regular veterinary monitoring — twice-yearly rather than annual — enables earlier treatment of secondary conditions before they become severe.