Cushing's disease (hyperadrenocorticism) is a common endocrine disorder in older dogs that causes wide-ranging physical symptoms and significant welfare impacts if untreated.
Cushing's disease causes chronic discomfort through muscle weakness, skin thinning and infection, pot-belly causing postural difficulties, and increased susceptibility to urinary tract infections. Dogs may appear lethargic and show reduced interest in activities they previously enjoyed. The condition also increases thirst dramatically, leading to indoor urination accidents that can cause stress through scolding or disrupted routines. With appropriate medical management, most dogs achieve good quality of life, but owners need careful guidance on recognising early signs and monitoring medication side effects, particularly Addisonian crisis risk from over-treatment.