Feline hyperesthesia syndrome is a poorly understood neurological condition causing episodes of apparent pain, distress, and compulsive behavior in affected cats.
Feline hyperesthesia syndrome causes genuine episodic suffering that can significantly impair affected cats' quality of life. During episodes, cats appear to experience intense discomfort — whether neuropathic pain, intense itch, or seizure-related phenomena. The distressing nature of episodes, including self-directed biting and apparent inability to escape their own skin, indicates real welfare impact. Many cases go undiagnosed or are misattributed to behavioral problems. The therapeutic landscape is improving: medications that address both neurological and anxiety components often reduce episode frequency and severity significantly. Identifying and reducing environmental stressors is an important adjunct to medical treatment.