Cushing's disease causes excess cortisol production in dogs, leading to a characteristic range of symptoms. While manageable, it requires long-term veterinary commitment and careful monitoring.
Cushing's disease imposes a significant welfare burden through its systemic effects on metabolism, immune function, and physical comfort. The pot-bellied abdomen, skin changes, and muscle weakness progressively impair mobility and body condition. Chronic excess cortisol suppresses immune function, predisposing affected dogs to skin infections, urinary tract infections, and other opportunistic conditions. The psychological effects of polyuria and polydipsia, including accidents in the house that distress both dog and owner, add to the welfare impact. With appropriate diagnosis and careful long-term management, many dogs with Cushing's disease can maintain good quality of life for years. Owner education about the need for regular monitoring and emergency awareness of adrenal crises is essential.