Hyperthyroidism is the most common endocrine disease of older cats, causing significant welfare impacts if untreated.
Untreated hyperthyroidism causes sustained physiological stress — elevated heart rate, hypertension, weight loss despite hyperphagia, and gastrointestinal disruption — that significantly impairs quality of life. Cats often appear superficially well because their appetite and activity are maintained, delaying diagnosis. Welfare-centred care involves annual thyroid screening for cats over 9 years, prompt treatment when diagnosed, and ongoing monitoring for treatment side effects and concurrent conditions. Methimazole provides effective control but requires lifelong administration; radioactive iodine offers a one-time curative option that, where accessible, provides the best long-term welfare outcome.