Feline leukemia virus (FeLV) is a serious retroviral infection that suppresses the immune system and causes cancer, but is preventable through vaccination and management.
FeLV infection causes progressive, ultimately fatal immune compromise in most affected cats. Unlike FIV, FeLV is more readily transmitted through casual contact — shared resources, grooming and bite wounds all represent transmission routes. FeLV-positive cats can live comfortable lives for variable periods, but their welfare requires active management of secondary infections and careful monitoring for cancer development. Vaccination is highly effective and should be a routine component of preventive care for all cats with outdoor access or exposure to other cats of unknown status. Testing new cats before introduction to an established household prevents transmission.