Feline hyperesthesia syndrome causes episodes of skin sensitivity, self-directed aggression, and distress in affected cats, requiring careful diagnosis and multimodal management.
Cats with hyperesthesia syndrome experience episodes of apparent distress involving intense skin sensitivity, self-mutilation, and disorientation that are clearly welfare-compromising. The syndrome is challenging because its pathophysiology is not fully understood, making targeted treatment difficult. Many cats are inadequately managed with environmental factors overlooked in favor of pharmacological approaches. A comprehensive assessment including dermatological evaluation, neurological assessment, and behavioral analysis is essential for effective welfare management.