Feline leukemia virus (FeLV) is a leading infectious cause of cat death worldwide. Vaccination and testing prevent transmission and allow welfare-focused management of positive cats.
FeLV infection causes progressive immune failure with secondary infections and cancers causing chronic suffering. Diagnosis is often delayed because early infection causes non-specific symptoms. FeLV-positive cats experience good quality of life during the regressive phase before immune compromise becomes significant, making welfare-focused management important rather than premature euthanasia. Indoor-only lifestyle protects both the positive cat from secondary infections and other cats from transmission through saliva. Multi-cat household management when a positive cat is diagnosed requires careful risk assessment and vaccination of all FeLV-negative housemates.