Adequate veterinary care, pain management, and humane endpoint policies are essential welfare requirements in animal research facilities.
Laboratory animal welfare depends critically on the quality of veterinary oversight and pain management. Under-recognition of animal pain — particularly in species that mask discomfort — leads to inadequate treatment. Humane endpoint criteria define the welfare threshold at which experiments must stop, preventing maximum-severity outcomes. Well-defined and consistently applied endpoint criteria, proactive pain assessment scoring systems, and appropriate analgesic protocols represent the most important veterinary welfare contributions to laboratory animal care.