Bovine respiratory disease complex is the most costly cattle disease globally and causes significant animal suffering — prevention and welfare implications.
BRD welfare is inseparable from stress management because stress is the primary gateway through which pathogens overwhelm immune defense. The feedlot system creates a concentrated BRD challenge by combining multiple stressors — weaning, transport, mixing with unfamiliar animals, new environments — in rapid succession. Each of these stressors can be individually mitigated: vaccination before transport, preconditioning programs that allow calves to adjust to weaning before feedlot entry, and low-stress transport and handling. The welfare and economic cases for BRD prevention are aligned — treatment is costly, mortality is costly, and growth suppression during illness is costly. Investing in prevention is both more humane and more economically rational than relying on treatment.