Cat vaccination protocols have evolved toward core and non-core categorization with evidence-based intervals, minimizing unnecessary procedures while maintaining protection against serious infectious diseases.
Cat vaccination decisions involve balancing the welfare benefit of disease protection against the welfare cost of veterinary visits, handling stress, and the small but real risk of injection-site sarcoma. Evidence-based vaccination protocols that provide appropriate protection with minimum necessary procedures align welfare and evidence. Annual revaccination for all vaccines, once standard practice, has given way to risk-based protocols that extend intervals for adult cats with established immunity and reduce non-core vaccine use to situations of genuine exposure risk. For cats with high veterinary handling stress, titer testing to confirm immunity before revaccination may avoid unnecessary procedures for animals with demonstrated protection. The welfare goal is maintaining genuine disease protection with minimum unnecessary procedures, not simply maximizing or minimizing vaccine use.