Chytridiomycosis caused by Batrachochytrium dendrobatidis has driven more amphibian species to extinction than any other disease in recorded history.
Chytridiomycosis causes disruption of skin function, electrolyte imbalance, cardiac failure, and death. Individual amphibians experience prolonged suffering during disease progression. At population level, the welfare implications are multiplied across millions of animals in wild populations. Conservation responses including captive breeding programs require attention to individual welfare — appropriate temperature, humidity, feeding, and disease screening must meet the specific requirements of threatened species, which vary enormously across the amphibian diversity of frogs, salamanders, and caecilians.