Vaccination has transformed salmon aquaculture welfare in Norway and Scotland by dramatically reducing antibiotic use and the disease burden driving it.
Salmon vaccination welfare is overwhelmingly positive — the diseases prevented cause far greater suffering than the vaccination procedure itself. Norwegian salmon aquaculture demonstrates what is possible when vaccination programs mature: near-elimination of antibiotic use and the disease-driven mass mortality events that cause widespread fish suffering. The residual welfare concern is injection site granuloma formation with some oil adjuvant vaccines, which causes localized inflammation and potential internal scarring. Vaccine formulation research aimed at reducing adjuvant-related pathology while maintaining efficacy addresses this remaining welfare concern.