Red squirrel populations in the UK have declined dramatically due to grey squirrel competition and squirrelpox, making conservation efforts inseparable from individual animal welfare considerations.
Squirrelpox causes severe individual suffering — the disease progression involves facial ulceration and ocular damage over 1-2 weeks before death. Each infection represents genuine welfare harm to an individual animal experiencing pain and distress. Conservation interventions including grey squirrel management reduce both individual squirrelpox mortality and population-level extinction risk. Vaccine development would eventually provide a welfare-positive alternative to continued lethal control.