Batrachochytrium dendrobatidis (Bd) chytrid fungus has caused the greatest vertebrate biodiversity loss in history; affected amphibians suffer severely.
Chytrid disease causes a slow, distressing death in affected amphibians. Skin function progressively deteriorates, disrupting the osmotic balance these animals depend on; as electrolyte imbalance develops, animals become lethargic, adopt abnormal postures, and experience cardiac failure. The scale of mortality from Bd since its emergence represents one of the largest acute animal welfare crises in recorded history. Conservation biosecurity — decontaminating equipment between sites, not transferring animals between water bodies, and preventing the international trade that spread Bd — is the primary welfare prevention measure. Probiotic treatments using beneficial bacteria are showing promise in some trials.