Pregnancy toxaemia (twin lamb disease) is a life-threatening metabolic condition in ewes carrying multiple lambs, causing significant welfare problems in sheep flocks.
Pregnancy toxaemia causes profound suffering including metabolic encephalopathy, hepatic fat infiltration, and organ failure if untreated. Affected ewes are unable to stand or eat and experience significant pain. Prevention is substantially more effective than treatment and requires systematic flock management: body condition scoring all ewes at tupping (target BCS 3-3.5), scanning to identify multiple-bearing ewes, and providing increased nutrition from 8 weeks pre-lambing. Treatment with propylene glycol, glucose infusions, and corticosteroids can be effective if initiated early. Welfare improvement programmes like the AHDB BETTER Returns Programme include pregnancy toxaemia prevention as a core module for UK sheep farmers.