Feline cognitive dysfunction syndrome (CDS) is an Alzheimer's-like condition in older cats causing disorientation, behavioural changes, and significant welfare impacts.
CDS significantly reduces quality of life in affected cats through disorientation, confusion, and anxiety. Nighttime vocalisation reflects disorientation and distress. Owners frequently mistake CDS signs for normal ageing, leading to underdiagnosis and undertreatment. Welfare management includes environmental enrichment (puzzle feeders, sensory stimulation), predictable routines to reduce disorientation anxiety, night lights to reduce fear during nocturnal confusion, and dietary supplements including omega-3 fatty acids and antioxidants. Selegiline (Anipryl) has evidence in dogs and may benefit some cats. Regular quality-of-life assessment is essential as CDS progresses — timely euthanasia prevents prolonged confusion and distress in advanced cases.