Allergen-specific immunotherapy offers long-term disease modification for dogs with atopic dermatitis, reducing itch and skin inflammation beyond the period of active treatment.
Canine atopic dermatitis causes chronic and severe pruritus that significantly impairs welfare through constant scratching, skin damage, secondary infections, and sleep disruption. Symptomatic treatments provide control but require lifelong administration and carry cumulative side effect risks. ASIT offers the prospect of meaningful long-term improvement in the underlying immune dysregulation. For dogs that respond, reductions in itch and skin inflammation are sustained and may allow reduction in symptomatic medication. The commitment required from owners is significant but justified by the welfare benefit of genuine disease modification.