Canine hypoadrenocorticism (Addison's disease) requires lifelong hormone replacement but allows excellent quality of life with proper management.
Addison's disease is well-managed with modern therapy, but owners must understand the importance of stress dosing — tripling prednisolone during illness or surgery to prevent crisis. Dogs on long-term therapy should have twice-yearly electrolyte checks and annual health assessments. Quality of life is generally excellent; most dogs lead normal, active lives. The main welfare risk is owner non-compliance with monitoring and stress-dosing protocols.