Horse Rhabdomyolysis Aftermath: Recovery and Prevention of Recurrence

Equine rhabdomyolysis (tying-up) causes acute muscle damage; long-term management is essential to prevent recurrence.

Key Facts

Rhabdomyolysis ranges from mild stiffness to severe muscle necrosis with myoglobinuria and renal risk.
Recurrent Exertional Rhabdomyolysis (RER) and Polysaccharide Storage Myopathy (PSSM) are the main chronic forms.
Genetic testing identifies PSSM1 caused by the GYS1 mutation; PSSM2 has complex genetics.
Dietary management — low starch, high fat — is central to PSSM management.
Regular low-intensity exercise reduces episodes in RER-affected horses; irregular work increases risk.
Electrolyte supplementation and vitamin E/selenium are part of many management programmes.

Welfare Considerations

Acute rhabdomyolysis causes intense muscle pain and distress. Horses experiencing severe episodes may be unable to move and require IV fluid therapy and pain management. Chronic management must prevent recurrence while maintaining the horse in regular, enjoyable work. Dietary and exercise programme changes that successfully prevent episodes dramatically improve quality of life for both horse and owner.

What You Can Do

Genetic test horses with recurrent tying-up for PSSM1 — results guide dietary management.
Maintain a consistent daily exercise regime even on rest days with turnout or in-hand walking.
Feed a low-starch, high-fat diet for PSSM horses — avoid cereal-based competition feeds.
Discuss blood monitoring of muscle enzymes (CK, AST) with your vet to track muscle health.