Cat Pancreatitis Diagnosis: When to Suspect and Test

Feline pancreatitis is often underdiagnosed because clinical signs are non-specific; awareness of diagnostic options improves welfare outcomes.

Key Facts

Feline pancreatitis presents with anorexia, lethargy, and vomiting — signs common to many conditions.
Spec fPL (feline pancreatic lipase) is the most sensitive and specific serum test for acute pancreatitis.
Ultrasound may reveal pancreatic oedema, masses, or associated fluid, but is insensitive for mild disease.
Pancreatitis in cats is frequently concurrent with IBD and cholangitis (the "triaditis" complex).
Chronic pancreatitis may present with intermittent mild signs — weight loss, occasional vomiting — that are easy to dismiss.
Trypsin-like immunoreactivity (TLI) assay detects exocrine pancreatic insufficiency secondary to chronic pancreatitis.

Welfare Considerations

Underdiagnosis of pancreatitis means affected cats suffer chronic or recurrent discomfort without specific treatment. Any cat with recurrent vomiting, weight loss, or intermittent anorexia should have Spec fPL measured as part of the diagnostic workup. Concurrent IBD and cholangitis require coordinated management. Early diagnosis and appropriate treatment — including pain management — significantly improves welfare outcomes for this commonly missed condition.

What You Can Do

Request Spec fPL testing for any cat with recurrent vomiting, anorexia, or unexplained weight loss.
Inform your vet if your cat has a known IBD or liver disease diagnosis — pancreatitis screening is warranted.
Feed multiple small meals of highly palatable food during pancreatitis recovery.
Ask about pain assessment and analgesic provision for cats diagnosed with acute pancreatitis.