Feline megacolon causes chronic constipation and eventual obstipation. Long-term management requires a combination of dietary, medical and sometimes surgical intervention.
Cats with megacolon experience distress and discomfort from persistent straining and the accumulation of retained faeces. Obstipation — complete failure of defecation — requires veterinary deobstipation under anaesthesia, which carries risk in debilitated animals. Long-term welfare depends on owner commitment to daily laxative dosing, high-moisture diet, regular monitoring and prompt recognition of deterioration. Subtotal colectomy has excellent outcomes in appropriate candidates, providing effective cure with adaptation of the shortened colon over several months.