FeLV is a serious retroviral infection causing immune dysfunction and cancer in cats. Prevention through vaccination and testing protects individual cats and reduces transmission.
FeLV infection progresses through several phases with ultimate development of progressive immune suppression leaving cats vulnerable to secondary infections, immune-mediated disease, and lymphoma. The welfare course of FeLV-positive cats varies significantly, with some maintaining good quality of life for extended periods while others deteriorate more rapidly. Welfare management focuses on minimizing stress to reduce immunosuppression, prompt treatment of secondary infections, monitoring for lymphoma development, and ensuring excellent nutrition. Indoor management protects both the FeLV-positive cat from infections and other cats from transmission. The decision about euthanasia must be based on quality of life assessment.