Canine infectious hepatitis caused by canine adenovirus type 1 is a serious liver disease prevented by core vaccination and rarely seen in well-vaccinated dog populations.
Canine infectious hepatitis causes acute hepatic failure with severe suffering from vomiting, abdominal pain, jaundice, and haemorrhage. Surviving dogs may develop chronic corneal oedema causing discomfort and vision impairment. Peracute cases die within hours. The welfare impact of hepatitis is severe but almost entirely preventable through vaccination. The rarity of the disease in vaccinated populations demonstrates the welfare value of core vaccination programmes.