Spotted-tailed quolls are Australia's largest marsupial carnivore facing fox and cat predation alongside habitat loss.
Spotted-tailed quoll welfare is threatened by fox and cat predation causing violent deaths. Habitat loss reduces access to hollow log dens that provide shelter and breeding sites. Poisoning baits designed for foxes and cats occasionally affect quolls through secondary poisoning of carcasses. Road mortality is an increasing concern as habitat is fragmented by road networks. Predator-free islands and sanctuaries provide welfare environments allowing natural behavior without constant predation pressure.