Leptospirosis is a serious bacterial disease in dogs transmitted through contact with infected water or wildlife urine, capable of causing fatal kidney and liver failure, and transmissible to humans.
Dogs with severe leptospirosis suffer from the combined effects of kidney failure, liver failure, and systemic infection. Jaundice, intense nausea, muscle pain, and profound weakness characterize severe cases. The renal failure component causes metabolic toxin accumulation that leads to vomiting, lethargy, and eventually neurological signs. Affected dogs require intensive hospitalization with IV fluids, antibiotics, and supportive care for days to weeks. Despite treatment, some dogs die or develop permanent chronic kidney disease. Dogs that survive severe leptospirosis may require ongoing management for residual organ damage. Prevention through vaccination is straightforward and highly effective, making unvaccinated dog leptospirosis a preventable welfare failure.