Feline hyperesthesia syndrome is a poorly understood condition causing skin hypersensitivity, bizarre behavioral episodes, and self-directed aggression that significantly compromises welfare.
Feline hyperesthesia syndrome causes significant suffering during episodes through the intense discomfort of skin hypersensitivity and the distressing behavioral manifestations that accompany attacks. Cats appear frightened during episodes, with dilated pupils and frantic behavior suggesting they are experiencing an uncomfortable or aversive internal state. Self-directed aggression during severe episodes causes physical injury. The episodic nature means cats may have good periods between attacks, but the unpredictability of triggers creates ongoing anxiety in affected animals. Stress reduction is a key management component, suggesting that anxiety contributes to episode frequency. Treatment with appropriate medications can substantially reduce episode frequency and severity, improving overall quality of life for affected cats.