Coccidioidomycosis from endemic soil fungi poses a growing welfare threat to cats in expanding southwestern US regions as climate change widens the endemic zone.
Cats with disseminated valley fever suffer from multiple system involvement including chronic respiratory disease, painful osteomyelitis from bone lesions, and the systemic effects of profound fungal infection. The diagnostic challenge of distinguishing valley fever from neoplasia and other causes of weight loss means many cats are treated for the wrong condition. Welfare is also affected by the prolonged nature of treatment, requiring long-term antifungal medication. Geographic expansion of endemic zones means veterinarians in non-traditional areas may lack familiarity with valley fever presentations, further delaying diagnosis and treatment.