Chronic kidney disease is the leading cause of death in older cats, requiring evidence-based management to extend both lifespan and quality of life.
Cats with CKD experience the accumulated burden of uremia including nausea, reduced appetite, weight loss, weakness, and dehydration. The insidious onset means many cats experience months of chronic malaise before diagnosis. Welfare-centered management focuses on maintaining adequate hydration, controlling phosphate absorption, managing nausea and inappetence, and monitoring blood pressure for hypertensive complications. Home subcutaneous fluid therapy, while initially daunting for owners, dramatically improves hydration and wellbeing in cats with advanced disease. The goal of CKD management is quality of life preservation, requiring honest ongoing conversations with veterinarians about when medical intervention benefits outweigh burden for individual cats.