IMHA is a life-threatening autoimmune condition where the immune system destroys red blood cells, requiring urgent treatment and careful welfare monitoring throughout recovery.
Dogs with acute IMHA experience profound weakness from hypoxia as their red blood cell count crashes - equivalent to extreme exhaustion from severe blood loss. Jaundice from hemoglobin breakdown causes additional systemic illness. Hospitalization with oxygen supplementation, transfusions, and multiple medications creates significant welfare burden from repeated procedures. Dogs who survive the acute crisis typically recover well but face a 30-40% relapse rate requiring lifelong owner vigilance.