Pituitary pars intermedia dysfunction (PPID), commonly called equine Cushing's disease, is common in older horses and ponies. Effective management improves quality of life significantly.
Untreated PPID causes progressive deterioration in quality of life. The abnormally long coat causes year-round thermal discomfort, muscle wasting reduces mobility and physical capacity, and laminitis causes severe chronic foot pain. Many horses suffer significantly before diagnosis because the condition develops gradually. Effective treatment with pergolide can reverse most symptoms within months, representing a significant welfare improvement. Regular veterinary monitoring allows dose adjustment and early intervention when disease progresses.