Cushing's disease in dogs involves chronic cortisol excess that profoundly affects quality of life, but with appropriate management most dogs can be stabilized and maintained comfortably for years.
Cushing's disease creates cumulative, insidious welfare impacts: affected dogs become progressively weaker, more susceptible to infection, and increasingly uncomfortable as cortisol excess degrades muscle, skin, and immune function. Many owners do not recognize early signs as disease rather than normal aging, delaying diagnosis and treatment. The pot-bellied appearance from muscle wasting and fat redistribution is often viewed aesthetically rather than medically. Treatment requires careful dose calibration with regular monitoring to prevent dangerous cortisol crashes (Addisonian crises), creating an ongoing welfare management challenge. Well-managed dogs show remarkable improvement - returning to more normal energy, coat condition, and comfort. Access to treatment is limited by cost; many dogs with Cushing's receive no treatment or delayed treatment due to the expense of both diagnostics and long-term medication.