West Nile virus causes fatal neurological disease in unvaccinated horses, with vaccination providing highly effective and welfare-important protection.
West Nile encephalitis causes profound neurological suffering - horses in acute disease show incoordination, muscle tremors, inability to stand, and severe distress. Many affected horses must be euthanized on welfare grounds. The suffering is entirely preventable through vaccination. For horse owners in or near endemic areas, WNV vaccination is as much a welfare obligation as feeding and watering. The cost-benefit analysis is overwhelming in favor of prevention.