Over-grooming leading to self-induced alopecia in cats is usually a stress response requiring environmental modification and behavior-focused management.
Over-grooming reflects genuine anxiety in cats - the repetitive behavior provides stress relief in the way that other repetitive behaviors serve as coping mechanisms. The hair loss itself causes secondary skin vulnerability, but the primary welfare concern is the chronic stress state driving the behavior. Identifying and addressing environmental stressors - inter-cat conflict, inadequate hiding spaces, unpredictable routines - reduces the anxiety causing the behavior. Medication supports behavioral management but does not replace the need to address the underlying stressor.