Liver fluke (Fasciola hepatica) causes significant welfare harm and production losses in cattle and sheep. Strategic control programs reduce the welfare burden of this prevalent parasitic disease.
Liver fluke welfare impact is most significant in the subclinical majority: animals losing body condition, milk production, and immune competence from fluke burdens that do not cause obvious clinical disease. These animals are suffering welfare impairment that is invisible without appropriate monitoring and treatment programs. The emerging triclabendazole resistance problem adds complexity: treatments that were once reliably effective may not kill all fluke stages in affected regions, requiring flukicide resistance testing and alternative treatment planning. A strategic approach that uses regional risk information, appropriate flukicide timing, and monitoring through liver condemnation data provides much better welfare outcomes than reactive treatment of clinical cases only.