Housing standards for laboratory animals significantly affect their welfare, with evidence-based improvements in enrichment and social housing now widely implemented.
Laboratory animal housing welfare has improved substantially as welfare science has been applied to research animal care. Recognition that social isolation of naturally gregarious species like mice and rats causes chronic stress - comparable to pain as a welfare stressor - has driven shifts to group housing. Provision of nesting material, which mice use instinctively and persistently, is now standard in many facilities. The evidence base for housing welfare improvements demonstrates that better welfare does not compromise research quality - in many cases it improves reproducibility by reducing stress-related biological variability.